A combination of transcriptome and methylation analyses reveals embryologically-relevant candidate genes in MRKH patients
نویسندگان
چکیده
منابع مشابه
A combination of transcriptome and methylation analyses reveals embryologically-relevant candidate genes in MRKH patients
BACKGROUND The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is present in at least 1 out of 4,500 female live births and is the second most common cause for primary amenorrhea. It is characterized by vaginal and uterine aplasia in an XX individual with normal secondary characteristics. It has long been considered a sporadic anomaly, but familial clustering occurs. Several candidate genes have...
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ژورنال
عنوان ژورنال: Orphanet Journal of Rare Diseases
سال: 2011
ISSN: 1750-1172
DOI: 10.1186/1750-1172-6-32